タイトル | Notum Deacylates Wnt Proteins to Suppress Signalling Activity. |
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ジャーナル・号・ページ | Nature, Vol. 519, Page 187-, Year 2015 |
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掲載日 | 2014年9月3日 (構造データの登録日) |
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著者 | Kakugawa, S. / Langton, P.F. / Zebisch, M. / Howell, S.A. / Chang, T. / Liu, Y. / Feizi, T. / Bineva, G. / O'Reilly, N. / Snijders, A.P. ...Kakugawa, S. / Langton, P.F. / Zebisch, M. / Howell, S.A. / Chang, T. / Liu, Y. / Feizi, T. / Bineva, G. / O'Reilly, N. / Snijders, A.P. / Jones, E.Y. / Vincent, J. |
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リンク | Nature / PubMed:25731175 |
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手法 | X線回折 |
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解像度 | 1.4 - 2.8 Å |
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構造データ | PDB-4uyu: STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I IODIDE COMPLEX - 2.3A 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-4uyw: STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I HEPARIN FRAGMENT COMPLEX - 1.7A 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-4uyz: STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM II - 2.8A 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4uz1: STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM III - 1.4A 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-4uz5: STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM IV - 2.1A 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-4uz6: STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM V - SOS COMPLEX - 1.9A 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-4uz7: STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VI - 2.2A 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-4uz9: STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VII - SOS COMPLEX - 2.2A 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-4uza: STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VIII - PHOSPHATE COMPLEX - 2.4A 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-4uzj: STRUCTURE OF THE WNT DEACYLASE NOTUM FROM DROSOPHILA - CRYSTAL FORM I - 2.4A 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-4uzk: STRUCTURE OF THE WNT DEACYLASE NOTUM FROM DROSOPHILA - CRYSTAL FORM II - 1.9A 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-4uzl: STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I MYRISTOLEATE COMPLEX - 2.1A 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-4uzq: STRUCTURE OF THE WNT DEACYLASE NOTUM IN COMPLEX WITH O-PALMITOLEOYL SERINE - CRYSTAL FORM IX - 1.5A 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-4wbh: STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I APO - 2.2A 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å |
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化合物 | |
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由来 | - homo sapiens (ヒト)
- drosophila melanogaster (キイロショウジョウバエ)
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キーワード | HYDROLASE / ESTERASE / EXTRACELLULAR / ALPHA/BETA HYDROLASE / WNT / extracellular Esterase |
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