EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
ジャーナル・号・ページ	Plos One, Vol. 8, Page 65689-, Year 2013
掲載日	2012年10月5日 (構造データの登録日)
著者	Silva-Santisteban, M.C. / Westwood, I.M. / Boxall, K. / Brown, N. / Peacock, S. / Mcandrew, C. / Barrie, E. / Richards, M. / Mirza, A. / Oliver, A.W. ...Silva-Santisteban, M.C. / Westwood, I.M. / Boxall, K. / Brown, N. / Peacock, S. / Mcandrew, C. / Barrie, E. / Richards, M. / Mirza, A. / Oliver, A.W. / Burke, R. / Hoelder, S. / Jones, K. / Aherne, G.W. / Blagg, J. / Collins, I. / Garrett, M.D. / Van Montfort, R.L.
リンク	Plos One / PubMed:23776527
手法	X線回折
解像度	2.32 - 3.3 Å
構造データ	PDB-4bda: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-4bdb: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-4bdc: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 手法: X-RAY DIFFRACTION / 解像度: 3 Å PDB-4bdd: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 手法: X-RAY DIFFRACTION / 解像度: 2.67 Å PDB-4bde: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 手法: X-RAY DIFFRACTION / 解像度: 2.55 Å PDB-4bdf: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4bdg: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 手法: X-RAY DIFFRACTION / 解像度: 2.84 Å PDB-4bdh: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4bdi: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 手法: X-RAY DIFFRACTION / 解像度: 2.32 Å PDB-4bdj: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 手法: X-RAY DIFFRACTION / 解像度: 3.01 Å PDB-4bdk: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 手法: X-RAY DIFFRACTION / 解像度: 3.3 Å
化合物	ChemComp-NO3: NITRATE ION / 硝酸塩 ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル / エチレングリコール ChemComp-VFB: 3,4-dihydro[1,2,4]triazolo[1,5-a][3,1]benzimidazol-9-ium ChemComp-CL: Unknown entry / クロリド / 塩化物 ChemComp-HOH: WATER / 水 ChemComp-ODO: 4-[(E)-C-methyl-N-oxidanyl-carbonimidoyl]benzene-1,3-diol / 2′,4′-ジヒドロキシアセトフェノンオキシム ChemComp-ODH: N-(furan-2-ylmethyl)quinoxaline-6-carboxamide ChemComp-Z0O: 1-(TERT-BUTYL)-3-(QUINOXALIN-6-YL)UREA ChemComp-CWS: 6-METHYLQUINAZOLIN-4-AMINE / 6-メチルキナゾリン-4-アミン ChemComp-H3R: 5-METHYL-3-PHENYL-1H-PYRAZOLE / 3-フェニル-5-メチル-1H-ピラゾ-ル ChemComp-P3J: 3-(PYRIDIN-3-YL)-1H-PYRAZOL-5-AMINE / 3-(3-ピリジニル)-1H-ピラゾ-ル-5-アミン ChemComp-WVI: 3-METHYL-4-(THIOPHEN-2-YL)-1H-PYRAZOL-5-AMINE ChemComp-HAU: 1-acetyl-N-(5-methylpyridin-2-yl)piperidine-4-carboxamide ChemComp-Z2M: 3-cyclopropyl-4-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridine ChemComp-RQQ: N-[(4-methoxyphenyl)methyl]quinoxaline-6-carboxamide
由来	homo sapiens (ヒト)
キーワード	TRANSFERASE (転移酵素) / INHIBITOR (酵素阻害剤)