EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme.
ジャーナル・号・ページ	Biochemistry, Vol. 51, Page 8665-8678, Year 2012
掲載日	2010年1月23日 (構造データの登録日)
著者	Desai, B.J. / Wood, B.M. / Fedorov, A.A. / Fedorov, E.V. / Goryanova, B. / Amyes, T.L. / Richard, J.P. / Almo, S.C. / Gerlt, J.A.
リンク	Biochemistry / PubMed:23030629
手法	X線回折
解像度	1.26 - 1.9411 Å
構造データ	PDB-3li0: Crystal structure of the mutant R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-3p5y: Crystal structure of the mutant T159A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-3p5z: Crystal structure of the mutant T159S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.3 Å PDB-3p60: Crystal structure of the mutant T159V of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-3p61: Crystal structure of the mutant R160A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.396 Å PDB-3qez: Crystal structure of the mutant T159V,V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.5431 Å PDB-3qf0: Crystal structure of the mutant T159V,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.34 Å PDB-3qmr: Crystal structure of the mutant R160A,V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.3213 Å PDB-3qms: Crystal structure of the mutant T159V,V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.32 Å PDB-3qmt: Crystal structure of the mutant V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.3202 Å PDB-3rlu: Crystal structure of the mutant K82A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.49 Å PDB-3rlv: Crystal structure of the mutant Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.421 Å PDB-3sj3: Crystal structure of the mutant R160A.Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.26 Å PDB-3v1p: Crystal structure of the mutant Q185A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.37 Å PDB-4fx6: Crystal structure of the mutant V182A.R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.531 Å PDB-4fx8: Crystal structure of the mutant Q185A.R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.9411 Å PDB-4fxr: Crystal structure of the mutant T159V.R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.708 Å PDB-4gc4: Crystal structure of the mutant R160A.R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 手法: X-RAY DIFFRACTION / 解像度: 1.4204 Å
化合物	ChemComp-BMQ: 1-(5'-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC ACID / 1-(5′-ホスホ-β-D-リボフラノシル)バルビツル酸 ChemComp-HOH: WATER ChemComp-BMP: 6-HYDROXYURIDINE-5'-PHOSPHATE / 6-ヒドロキシウリジン5′-りん酸 ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-POL: N-PROPANOL / プロパノ-ル ChemComp-SO4: SULFATE ION / 硫酸ジアニオン
由来	methanothermobacter thermautotrophicus (古細菌) methanobacterium thermoautotrophicum (古細菌) methanothermobacter thermautotrophicus str. delta h (古細菌)
キーワード	LYASE / mutant R203A / 6-hydroxyuridine-5'-phosphate / Decarboxylase / Pyrimidine biosynthesis / tim barrel / orotidine 5'-monophosphate decarboxylase / inhibitor BMP / LYASE/LYASE INHIBITOR / (beta-alpha)8 barrel / LYASE-LYASE INHIBITOR complex / tim barrel fold / 5'-monophosphate decarboxylase