EMDB/PDB/SASBDBから引用されている文献のデータベース

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構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
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IF	>30 >20 >10 >5 all

タイトル	Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation.
ジャーナル・号・ページ	Nat Microbiol, Vol. 5, Issue 7, Page 966-975, Year 2020
掲載日	2020年4月13日
著者	Steven Johnson / Yu Hang Fong / Justin C Deme / Emily J Furlong / Lucas Kuhlen / Susan M Lea /
PubMed 要旨	The bacterial flagellum is a complex self-assembling nanomachine that confers motility to the cell. Despite great variation across species, all flagella are ultimately constructed from a helical ...The bacterial flagellum is a complex self-assembling nanomachine that confers motility to the cell. Despite great variation across species, all flagella are ultimately constructed from a helical propeller that is attached to a motor embedded in the inner membrane. The motor consists of a series of stator units surrounding a central rotor made up of two ring complexes, the MS-ring and the C-ring. Despite many studies, high-resolution structural information is still lacking for the MS-ring of the rotor, and proposed mismatches in stoichiometry between the two rings have long provided a source of confusion for the field. Here, we present structures of the Salmonella MS-ring, revealing a high level of variation in inter- and intrachain symmetry that provides a structural explanation for the ability of the MS-ring to function as a complex and elegant interface between the two main functions of the flagellum-protein secretion and rotation.
リンク	Nat Microbiol / PubMed:32284565 / PubMed Central
手法	EM (単粒子)
解像度	2.6 - 4.5 Å
構造データ	10143 6scn EMDB-10143, PDB-6scn: 33mer structure of the Salmonella flagella MS-ring protein FliF 手法: EM (単粒子) / 解像度: 3.1 Å 10145 6sd1 EMDB-10145, PDB-6sd1: Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 33-fold symmetry applied 手法: EM (単粒子) / 解像度: 2.6 Å 10146 6sd2 EMDB-10146, PDB-6sd2: Structure of the RBM2inner region of the Salmonella flagella MS-ring protein FliF with 21-fold symmetry applied. 手法: EM (単粒子) / 解像度: 3.1 Å 10147 6sd3 EMDB-10147, PDB-6sd3: 34mer structure of the Salmonella flagella MS-ring protein FliF 手法: EM (単粒子) / 解像度: 3.3 Å 10148 6sd4 EMDB-10148, PDB-6sd4: Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 34-fold symmetry applied 手法: EM (単粒子) / 解像度: 2.8 Å 10149 6sd5 EMDB-10149, PDB-6sd5: Structure of the RBM2 inner ring of Salmonella flagella MS-ring protein FliF with 22-fold symmetry applied 手法: EM (単粒子) / 解像度: 3.1 Å 10560 6tre EMDB-10560, PDB-6tre: Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 32-fold symmetry applied 手法: EM (単粒子) / 解像度: 3.3 Å EMDB-10561: Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 35-fold symmetry applied 手法: EM (単粒子) / 解像度: 4.5 Å
由来	salmonella enterica subsp. enterica serovar typhimurium (サルモネラ菌) salmonella typhimurium (サルモネラ菌)
キーワード	MOTOR PROTEIN / Flagella / Secretion / Rotor / MS-ring / C-ring / T3SS