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-Structure paper
Title | Identification of LY3522348: A Highly Selective and Orally Efficacious Ketohexokinase Inhibitor. |
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Journal, issue, pages | J. Med. Chem., Vol. 66, Page 15960-15976, Year 2023 |
Publish date | Oct 5, 2023 (structure data deposition date) |
Authors | Durham, T.B. / Hao, J. / Spinazze, P. / Stack, D.R. / Toth, J.L. / Massey, S. / Mbofana, C.T. / Johnston, R.D. / Lineswala, J.P. / Wrobleski, A. ...Durham, T.B. / Hao, J. / Spinazze, P. / Stack, D.R. / Toth, J.L. / Massey, S. / Mbofana, C.T. / Johnston, R.D. / Lineswala, J.P. / Wrobleski, A. / Minguez, J.M. / Perez, C. / Smith, D.L. / Lamar, J. / Leon, R. / Corkins, C. / Durbin, J. / Tung, F. / Guo, S. / Linder, R.J. / Yumibe, N. / Wang, W. / MacKrell, J. / Antonellis, M. / Mascaro, B. |
External links | J. Med. Chem. / PubMed:37992274 |
Methods | X-ray diffraction |
Resolution | 1.99 - 2.02 Å |
Structure data | PDB-8ug1: PDB-8ug3: |
Chemicals | ChemComp-WNH: ChemComp-SO4: ChemComp-GOL: ChemComp-HOH: ChemComp-WRE: |
Source |
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Keywords | SUGAR BINDING PROTEIN / Inhibitor |