- PDB-8ug3: Crystal structure of KHK-C and compound 23 -
+
Open data
ID or keywords:
Loading...
-
Basic information
Entry
Database: PDB / ID: 8ug3
Title
Crystal structure of KHK-C and compound 23
Components
Ketohexokinase
Keywords
SUGAR BINDING PROTEIN / Inhibitor
Function / homology
Function and homology information
Essential fructosuria / ketohexokinase / Fructose catabolism / ketohexokinase activity / regulation of glycogen metabolic process / response to sucrose / response to fructose / fructose metabolic process / response to zinc ion / response to glucose ...Essential fructosuria / ketohexokinase / Fructose catabolism / ketohexokinase activity / regulation of glycogen metabolic process / response to sucrose / response to fructose / fructose metabolic process / response to zinc ion / response to glucose / response to insulin / extracellular exosome / ATP binding / cytoplasm / cytosol Similarity search - Function
Method to determine structure: MOLECULAR REPLACEMENT / Resolution: 2.02→39.38 Å / Cor.coef. Fo:Fc: 0.97 / Cor.coef. Fo:Fc free: 0.955 / SU B: 3.967 / SU ML: 0.104 / Cross valid method: THROUGHOUT / ESU R: 0.129 / ESU R Free: 0.128 / Stereochemistry target values: MAXIMUM LIKELIHOOD / Details: HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT
Rfactor
Num. reflection
% reflection
Selection details
Rfree
0.21573
3172
5 %
RANDOM
Rwork
0.17915
-
-
-
obs
0.18099
60230
99.87 %
-
Solvent computation
Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.2 Å / Solvent model: BABINET MODEL WITH MASK