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-Structure paper
Title | Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance. |
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Journal, issue, pages | Molecules, Vol. 25, Year 2020 |
Publish date | Apr 27, 2020 (structure data deposition date) |
Authors | Bertoletti, N. / Chan, A.H. / Schinazi, R.F. / Anderson, K.S. |
External links | Molecules / PubMed:33096918 |
Methods | X-ray diffraction |
Resolution | 2.53 - 2.73 Å |
Structure data | PDB-6wpf: PDB-6wph: PDB-6wpj: |
Chemicals | ChemComp-D4M: ChemComp-SO4: ChemComp-MG: ChemComp-D4T: ChemComp-GOL: ChemComp-HOH: ChemComp-43X: ChemComp-DGP: |
Source |
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Keywords | TRANSFERASE/DNA / Reverse Transcriptase / ternary complex / d4T / chain terminator / stereochemistry / TRANSFERASE / TRANSFERASE-DNA complex / Stavudine / (-)FTC / Emtricitabine |