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-Structure paper
Title | Extending the Half-Life of a Fab Fragment Through Generation of a Humanized Anti-Human Serum Albumin Fv Domain: An Investigation Into the Correlation between Affinity and Serum Half-Life. |
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Journal, issue, pages | Mabs, Vol. 8, Page 1336-, Year 2016 |
Publish date | Jan 28, 2016 (structure data deposition date) |
Authors | Adams, R. / Griffin, L. / Compson, J.E. / Jairaj, M. / Baker, T. / Ceska, T. / West, S. / Zaccheo, O. / Dave, E. / Lawson, A.D.G. ...Adams, R. / Griffin, L. / Compson, J.E. / Jairaj, M. / Baker, T. / Ceska, T. / West, S. / Zaccheo, O. / Dave, E. / Lawson, A.D.G. / Humphreys, D.P. / Heywood, S. |
External links | Mabs / PubMed:27315033 |
Methods | X-ray diffraction |
Resolution | 2.68 - 3.6 Å |
Structure data | PDB-5fuo: PDB-5fuz: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / ANTI-ALBUMIN / FAB FRAGMENT / SERUM HALF-LIFE / FCRN / HUMAN SERUM ALBUMIN |