+Search query
-Structure paper
Title | Identification and optimization of Azaindole based MAP4K1 Inhibitors and the discovery of BAY-405 |
---|---|
Journal, issue, pages | To Be Published |
Publish date | Jun 8, 2023 (structure data deposition date) |
Authors | Mowat, J. / Carretero, R. / Leder, G. / Aiguabella Font, N. / Neuhaus, R. / Berndt, S. / Guenther, J. / Friberg, A. / Schaefer, M. / Briem, H. ...Mowat, J. / Carretero, R. / Leder, G. / Aiguabella Font, N. / Neuhaus, R. / Berndt, S. / Guenther, J. / Friberg, A. / Schaefer, M. / Briem, H. / Raschke, M. / Miyatake Ondozabal, H. / Buchmann, B. / Boemer, U. / Hartung, I. / Offringa, R. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.8 Å |
Structure data | PDB-8par: PDB-8pas: PDB-8pau: PDB-8pav: PDB-8paw: |
Chemicals | ChemComp-GOL:
ChemComp-XON: ChemComp-HOH:
ChemComp-XOH:
ChemComp-XOR:
ChemComp-XOZ: ChemComp-CXS: ChemComp-ASP:
ChemComp-XQL: |
Source |
|
Keywords | TRANSFERASE / kinase / inhibitor / drug discovery |