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Structure paper

TitleA molecular switch orchestrates the export of human messenger RNA
Journal, issue, pagesTo Be Published
Publish dateNov 25, 2023 (structure data deposition date)
AuthorsHohmann U / Graf M / Brennecke J / Plaschka C
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.5 - 5.89 Å
Structure data

18977

8r7j

EMDB-18977, PDB-8r7j:
Cryo-EM structure of the human TREX-2 complex
Method: EM (single particle) / Resolution: 3.5 Å

18978

8r7k

EMDB-18978, PDB-8r7k:
Cryo-EM structure of the human UAP56 - TREX-2 complex
Method: EM (single particle) / Resolution: 3.5 Å

18979

8r7l

EMDB-18979, PDB-8r7l:
Cryo-EM structure of the human TREX complex
Method: EM (single particle) / Resolution: 4.12 Å

EMDB-18980: Structure of a human TREX complex (with the THO tetramer).
Method: EM (single particle) / Resolution: 5.89 Å

EMDB-18981: Structure of the human UAP56 RecA1 RecA2 - TREX-2 complex
Method: EM (single particle) / Resolution: 4.22 Å

Chemicals

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / mRNA export / nuclear pore basket

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