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Structure paper

TitleStructural and Antigenic Characterization of B Cell Mosaic Env Trimers
Journal, issue, pagesTo Be Published
Publish dateMay 25, 2022 (structure data deposition date)
AuthorsXian, Y. / Wilson, I.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.46 - 4.32 Å
Structure data

PDB-8d01:
The domain-swaped dimer of the HIV-1 CD4bs targeting antibody 21N13
Method: X-RAY DIFFRACTION / Resolution: 2.46 Å

PDB-8d50:
Crystal Structure of Mosaic HIV-1 Envelope (MosM3.1) in Complex with antibodies PGT124 and 35O22 at 4.3 Angstrom
Method: X-RAY DIFFRACTION / Resolution: 4.32 Å

PDB-8d53:
Crystal Structure of Mosaic HIV-1 Envelope (MosM3.3) in Complex with antibodies PGT124 and 35O22 at 3.25 Angstrom
Method: X-RAY DIFFRACTION / Resolution: 3.24 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-MAN:
alpha-D-mannopyranose

Source
  • macaca mulatta (Rhesus monkey)
  • human immunodeficiency virus 1
  • homo sapiens (human)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / HIV-1 CD4bs antibody / Domain swap dimer / VIRAL PROTEIN-IMMUNE SYSTEM complex / HIV-1 envelop protein / B cell targeting / mosaic design / VIRAL PROTEIN

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