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Author
Journal
IF

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Structure paper

TitleDevelopment of TRIM21 PROTAC molecules
Journal, issue, pagesTo Be Published
Publish dateFeb 26, 2025 (structure data deposition date)
AuthorsLuptak, J. / James, L.C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.043 - 2.462 Å
Structure data

PDB-9q9o:
TRIM21 PRYSPRY bound to compound 36
Method: X-RAY DIFFRACTION / Resolution: 2.462 Å

PDB-9q9p:
TRIM21 PRYSPRY bound to compound 37
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-9q9q:
TRIM21 PRYSPRY bound to compound 38
Method: X-RAY DIFFRACTION / Resolution: 2.253 Å

PDB-9q9r:
TRIM21 PRYSPRY bound to compound 209
Method: X-RAY DIFFRACTION / Resolution: 2.331 Å

PDB-9r40:
HaloTag bound to compound MRC71
Method: X-RAY DIFFRACTION / Resolution: 2.043 Å

Chemicals

PDB-1i4z:
THE CRYSTAL STRUCTURE OF PHASCOLOPSIS GOULDII L98Y METHEMERYTHRIN

PDB-1i4x:
STAPHYLOCOCCAL ENTEROTOXIN C2, MONOCLINIC FORM CRYSTALLIZED AT PH 8.0

ChemComp-HOH:
WATER

PDB-1i4y:
THE CRYSTAL STRUCTURE OF PHASCOLOPSIS GOULDII WILD TYPE METHEMERYTHRIN

PDB-1i4w:
THE CRYSTAL STRUCTURE OF THE TRANSCRIPTION FACTOR SC-MTTFB OFFERS INTRIGUING INSIGHTS INTO MITOCHONDRIAL TRANSCRIPTION

ChemComp-CL:
Unknown entry

PDB-1jc1:
CRYSTAL STRUCTURE ANALYSIS OF A REDOX-SENSITIVE GREEN FLUORESCENT PROTEIN VARIANT IN A OXIDIZED FORM

Source
  • homo sapiens (human)
  • rhodococcus sp. (in: high g+c gram-positive bacteria) (bacteria)
KeywordsLIGASE / TRIM21 / E3 ligase / PROTAC / PRYSPRY / Halotag

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