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TitleMechanistic Insights into the Interactions of Ras Subfamily GTPases with the SPN Domain of Autism-associated SHANK3.
Journal, issue, pagesChin. J. Chem., Vol. 38, Page 1635-1641, Year 2020
Publish dateMay 25, 2020 (structure data deposition date)
AuthorsXu, X.L. / Liu, J.P. / Wang, Y.L. / Wang, Y. / Gong, X. / Pan, L.F.
External linksChin. J. Chem. / Search PubMed
MethodsX-ray diffraction
Resolution2.28 - 2.39 Å
Structure data

PDB-7c7i:
Crystal structure of SHANK3 SPN domain in complex with GTP-bound Rap1b(E30D,K31E)
Method: X-RAY DIFFRACTION / Resolution: 2.28 Å

PDB-7c7j:
Crystal structure of SHANK3 SPN domain in complex with GTP-bound Rap1b(G12V,Q63E)
Method: X-RAY DIFFRACTION / Resolution: 2.39 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-CA:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / SHANK3 / Rap1b / SPN / Ras

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