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TitleStructural Insights into the Activation of Human Prostaglandin E2 Receptor EP1 Subtype by Prostaglandin E2
Journal, issue, pagesTo Be Published
Publish dateFeb 26, 2025 (structure data deposition date)
AuthorsMeng X / Xu Y / Xu HE
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.55 Å
Structure data

63571

9m1h

EMDB-63571, PDB-9m1h:
Cryo-EM structure of PGE2-EP1-Gq complex
Method: EM (single particle) / Resolution: 2.55 Å

Chemicals

ChemComp-P2E:
(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid / medication*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / GPCR / EP1 / PGE2 / Gq

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