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TitleCryo-EM structure of the QseG-QseE complex reveals an accessory protein-driven two-component system activation mechanism
Journal, issue, pagesMbio, Year 2025
Publish dateFeb 24, 2025 (structure data deposition date)
AuthorsGao X / Li GB / Gong PQ
External linksSearch PubMed
MethodsEM (single particle) / X-ray diffraction
Resolution2.1 - 3.9 Å
Structure data

63539

9m08

EMDB-63539, PDB-9m08:
Structure of outer membrane lipoprotein QseG and histidine kinase QseE complex
Method: EM (single particle) / Resolution: 3.9 Å

PDB-9m06:
Outer membrane lipoprotein QseG of Salmonella enterica serovar Typhimurium SL1344
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-9m07:
Histidine kinase QseE sensor domain of Salmonella Typhimurium SL1344
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • salmonella enterica subsp. enterica serovar typhimurium str. sl1344 (bacteria)
KeywordsSIGNALING PROTEIN / signal activation / Histidine kinase / complex

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