タイトル | Structural basis for allosteric regulation of mycobacterial guanosine 5'-monophosphate reductase with ATP and GTP. |
---|
ジャーナル・号・ページ | To Be Published |
---|
掲載日 | 2024年2月8日 (構造データの登録日) |
---|
著者 | Dolezal M / Knejzlik Z / Kouba T / Filimonenko A / Svachova H / Klima M / Pichova I |
---|
リンク | PubMedで検索 |
---|
手法 | EM (単粒子) |
---|
解像度 | 2.48 - 3.85 Å |
---|
構造データ | EMDB-19583, PDB-8ry0: CryoEM structure of M. smegmatis GMP reductase in complex with GMP at pH 6.6, extended conformation. 手法: EM (単粒子) / 解像度: 3.66 Å EMDB-19584, PDB-8ry1: CryoEM structure of M. smegmatis GMP reductase in complex with GMP at pH 6.6, compressed conformation. 手法: EM (単粒子) / 解像度: 3.85 Å EMDB-19585, PDB-8ry3: CryoEM structure of M. smegmatis GMP reductase in complex with GMP and GTP at pH 6.6, extended conformation I. 手法: EM (単粒子) / 解像度: 2.52 Å EMDB-19586, PDB-8ry4: CryoEM structure of M. smegmatis GMP reductase in complex with GMP and GTP at pH 6.6, extended conformation II. 手法: EM (単粒子) / 解像度: 3.72 Å EMDB-19587, PDB-8ry5: CryoEM structure of M. smegmatis GMP reductase in complex with GMP and ATP at pH 6.6, compressed conformation. 手法: EM (単粒子) / 解像度: 2.48 Å EMDB-19588, PDB-8ry6: CryoEM structure of M. smegmatis GMP reductase apoform at pH 6.6, extended conformation I. 手法: EM (単粒子) / 解像度: 3.22 Å EMDB-19589, PDB-8ry7: CryoEM structure of M. smegmatis GMP reductase apoform at pH 6.6, extended conformation II. 手法: EM (単粒子) / 解像度: 3.7 Å EMDB-19590, PDB-8ry8: CryoEM structure of M. smegmatis GMP reductase apoform at pH 7.8, extended conformation I. 手法: EM (単粒子) / 解像度: 2.96 Å EMDB-19591, PDB-8ry9: CryoEM structure of M. smegmatis GMP reductase apoform at pH 7.8, extended conformation II. 手法: EM (単粒子) / 解像度: 3.2 Å EMDB-19592, PDB-8rya: CryoEM structure of M. smegmatis GMP reductase apoform at pH 7.8, tetramer. 手法: EM (単粒子) / 解像度: 2.82 Å EMDB-19593, PDB-8ryb: CryoEM structure of M. smegmatis GMP reductase in complex with GMP at pH 7.8, extended conformation. 手法: EM (単粒子) / 解像度: 2.84 Å |
---|
化合物 | |
---|
由来 | mycolicibacterium smegmatis (バクテリア)
|
---|
キーワード | OXIDOREDUCTASE / GMP reductase / GuaB1 / CBS domain / Mycobacterium smegmatis |
---|