タイトル Structural basis for allosteric regulation of mycobacterial guanosine 5'-monophosphate reductase with ATP and GTP. ジャーナル・号・ページ To Be Published 掲載日 2024年2月8日 (構造データの登録日) 著者Dolezal M / Knejzlik Z / Kouba T / Filimonenko A / Svachova H / Klima M / Pichova I リンクPubMedで検索 手法 EM (単粒子) / X線回折 解像度 1.6 - 3.85 Å 構造データ EMDB-19583 , PDB-8ry0 : CryoEM structure of M. smegmatis GMP reductase in complex with GMP at pH 6.6, extended conformation.手法 : EM (単粒子) / 解像度 : 3.66 Å
EMDB-19584 , PDB-8ry1 : CryoEM structure of M. smegmatis GMP reductase in complex with GMP at pH 6.6, compressed conformation.手法 : EM (単粒子) / 解像度 : 3.85 Å
EMDB-19585 , PDB-8ry3 : CryoEM structure of M. smegmatis GMP reductase in complex with GMP and GTP at pH 6.6, extended conformation I.手法 : EM (単粒子) / 解像度 : 2.52 Å
EMDB-19586 , PDB-8ry4 : CryoEM structure of M. smegmatis GMP reductase in complex with GMP and GTP at pH 6.6, extended conformation II.手法 : EM (単粒子) / 解像度 : 3.72 Å
EMDB-19587 , PDB-8ry5 : CryoEM structure of M. smegmatis GMP reductase in complex with GMP and ATP at pH 6.6, compressed conformation.手法 : EM (単粒子) / 解像度 : 2.48 Å
EMDB-19588 , PDB-8ry6 : CryoEM structure of M. smegmatis GMP reductase apoform at pH 6.6, extended conformation I.手法 : EM (単粒子) / 解像度 : 3.22 Å
EMDB-19589 , PDB-8ry7 : CryoEM structure of M. smegmatis GMP reductase apoform at pH 6.6, extended conformation II.手法 : EM (単粒子) / 解像度 : 3.7 Å
EMDB-19590 , PDB-8ry8 : CryoEM structure of M. smegmatis GMP reductase apoform at pH 7.8, extended conformation I. 手法 : EM (単粒子) / 解像度 : 2.96 Å
EMDB-19591 , PDB-8ry9 : CryoEM structure of M. smegmatis GMP reductase apoform at pH 7.8, extended conformation II. 手法 : EM (単粒子) / 解像度 : 3.2 Å
EMDB-19592 , PDB-8rya : CryoEM structure of M. smegmatis GMP reductase apoform at pH 7.8, tetramer. 手法 : EM (単粒子) / 解像度 : 2.82 Å
EMDB-19593 , PDB-8ryb : CryoEM structure of M. smegmatis GMP reductase in complex with GMP at pH 7.8, extended conformation.手法 : EM (単粒子) / 解像度 : 2.84 Å
PDB-9hfz : 構造ビューア Crystal structure of M. smegmatis GMP reductase in complex with IMP. 手法 : X-RAY DIFFRACTION / 解像度 : 2.8 Å
PDB-9hg0 : 構造ビューア Crystal structure of M. smegmatis GMP reductase with XMP* intermidiate in complex with NADP+ and IMP.手法 : X-RAY DIFFRACTION / 解像度 : 2.1 Å
PDB-9hg1 : 構造ビューア Crystal structure of M. smegmatis GMP reductase in complex with GMP and ATP. 手法 : X-RAY DIFFRACTION / 解像度 : 2.3 Å
PDB-9hg2 : 構造ビューア Crystal structure of M. smegmatis GMP reductase in complex with IMP and ATP.手法 : X-RAY DIFFRACTION / 解像度 : 1.6 Å
PDB-9hg3 : 構造ビューア Crystal structure of M. smegmatis GMP reductase in complex with GMP and GTP. 手法 : X-RAY DIFFRACTION / 解像度 : 2.3 Å
化合物 ChemComp-GTP : 構造ビューア GUANOSINE-5'-TRIPHOSPHATE / GTP, エネルギー貯蔵分子*YM
ChemComp-ATP : 構造ビューア ADENOSINE-5'-TRIPHOSPHATE / ATP, エネルギー貯蔵分子*YM
ChemComp-NAP : 構造ビューア NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
由来 mycolicibacterium smegmatis (バクテリア) キーワード OXIDOREDUCTASE / GMP reductase / GuaB1 / CBS domain / Mycobacterium smegmatis