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Title | Engineered Imine Reductase for Larotrectinib Intermediate Manufacture |
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Journal, issue, pages | Acs Catalysis, Vol. 12, Page 14795-14803, Year 2022 |
Publish date | Jun 24, 2022 (structure data deposition date) |
Authors | Chen, Q. / Li, B.B. / Zhang, L. / Chen, X.R. / Zhu, X.X. / Chen, F.F. / Shi, M. / Chen, C.C. / Yang, Y. / Guo, R.T. ...Chen, Q. / Li, B.B. / Zhang, L. / Chen, X.R. / Zhu, X.X. / Chen, F.F. / Shi, M. / Chen, C.C. / Yang, Y. / Guo, R.T. / Liu, W. / Xu, J.H. / Zheng, G.W. |
External links | Acs Catalysis / Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.08 - 2.41 Å |
Structure data | PDB-7y8k: PDB-7y8l: PDB-7y8m: PDB-7y8n: |
Chemicals | ChemComp-HOH: ChemComp-NDP: ChemComp-4IS: ChemComp-NAP: ChemComp-Q0R: |
Source |
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Keywords | HYDROLASE / substrate binding / OXIDOREDUCTASE/INHIBITOR / OXIDOREDUCTASE-inhibitor complex / HYDROLASE/INHIBITOR / HYDROLASE-inhibitor complex |