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Structure paper

TitleSite-selective stabilization of the 14-3-3/tau protein-protein interaction
Journal, issue, pagesTo Be Published
Publish dateJun 20, 2024 (structure data deposition date)
AuthorsOberheide, A.O. / van den Oetelaar, M.C.M. / Scheele, J.J.A. / Ottmann, C. / Cossar, P. / Brunsveld, L. / Engelen, S.F.H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-9fs4:
Crystal structure of 14-3-3 sigma in complex with Tau pS214 peptide and covalent stabilizer LD12
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-TJ8:
2-bromanyl-4-(2-phenylimidazol-1-yl)benzaldehyde

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / 14-3-3 / tau / protein-protein interaction / covalent stabilization

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