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Structure paper

TitleHuman metapneumovirus-specific antibodies isolated from infected children target diverse epitopes and have prophylactic efficacy in mice
Journal, issue, pagesTo Be Published
Publish dateMay 23, 2025 (structure data deposition date)
AuthorsKhalil AM / Ghazi Esfahani B / Mousa J
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.61 - 3.94 Å
Structure data

70793

9os5

EMDB-70793, PDB-9os5:
Human antibody Fab MPV498 bound to hMPV B2 post-fusion F
Method: EM (single particle) / Resolution: 2.61 Å

71547

9pdx

EMDB-71547, PDB-9pdx:
Human antibody Fab MPV513 bound to hMPV DsCav-ES2
Method: EM (single particle) / Resolution: 3.94 Å

71548

9pdy

EMDB-71548, PDB-9pdy:
Human antibody Fab MPV510 bound to hMPV DsCav-ES2-IPDS F protein
Method: EM (single particle) / Resolution: 2.85 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human metapneumovirus
KeywordsIMMUNE SYSTEM / ANTIVIRAL PROTEIN / hMPV / Human respiratory disease / cryoem / human metapneumovirus / VIRAL PROTEIN/IMMUNE SYSTEM / VIRAL PROTEIN-IMMUNE SYSTEM complex

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