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TitleFrom Monomers to Oligomers: Structural Mechanism of Receptor-Triggered MyD88 Assembly in Innate Immune Signaling
Journal, issue, pagesBiorxiv, Year 2024
Publish dateSep 4, 2023 (structure data deposition date)
AuthorsKasai K / Imamura K / Uno M / Sekiyama N / Miyata T / Makino F / Yamada R / Takahashi Y / Kodera N / Namba K ...Kasai K / Imamura K / Uno M / Sekiyama N / Miyata T / Makino F / Yamada R / Takahashi Y / Kodera N / Namba K / Ohnishi H / Narita A / Konno H / Tochio H
External linksBiorxiv / Search PubMed
MethodsEM (single particle)
Resolution3.28 - 3.3 Å
Structure data

37355

8w8m

EMDB-37355, PDB-8w8m:
Cryo-EM structure of helical filament of MyD88 TIR
Method: EM (single particle) / Resolution: 3.28 Å

39676

8yym

EMDB-39676, PDB-8yym:
Cryo-EM structure of cylindrical fiber of MyD88 TIR
Method: EM (single particle) / Resolution: 3.3 Å

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / signaling protein / innate immunity

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