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TitleCrystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA.
Journal, issue, pagesScience, Vol. 279, Page 1504-1513, Year 1998
Publish dateJan 27, 1998 (structure data deposition date)
AuthorsRedinbo, M.R. / Stewart, L. / Kuhn, P. / Champoux, J.J. / Hol, W.G.
External linksScience / PubMed:9488644
MethodsX-ray diffraction
Resolution2.1 - 2.5 Å
Structure data

PDB-1a31:
HUMAN RECONSTITUTED DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-1a35:
HUMAN TOPOISOMERASE I/DNA COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE/DNA / TOPOISOMERASE I/DNA / DNA / TOPOISOMERASE I / ISOMERASE-DNA COMPLEX / TOPOISOMERASE I/DNA)

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