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Structure paper

TitleStructural basis of affinity maturation of anti-(4-hydroxy-3-nitrophenyl)acetyl antibodies.
Journal, issue, pagesArch. Biochem. Biophys., Vol. 775, Page 110665-110665, Year 2026
Publish dateApr 7, 2025 (structure data deposition date)
AuthorsYoshida, M. / Hanazono, Y. / Numoto, N. / Yabuno, S. / Ito, N. / Azuma, T. / Oda, M.
External linksArch. Biochem. Biophys. / PubMed:41161463
MethodsX-ray diffraction
Resolution1.06 - 1.99 Å
Structure data

PDB-9udn:
Single-chain Fv antibody of F8
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

PDB-9udo:
Single-chain Fv antibody of F8 complex with NNP-Cap
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

PDB-9udp:
Single-chain Fv antibody of B2
Method: X-RAY DIFFRACTION / Resolution: 1.48 Å

PDB-9udr:
Single-chain Fv antibody of B2 complex with NP-glycine
Method: X-RAY DIFFRACTION / Resolution: 1.34 Å

PDB-9uds:
Single-chain Fv antibody of C6
Method: X-RAY DIFFRACTION / Resolution: 1.99 Å

PDB-9udt:
Single-chain Fv antibody of C6 complex with NNP-Cap
Method: X-RAY DIFFRACTION / Resolution: 1.08 Å

PDB-9udu:
Single-chain Fv antibody of E11 complex with NNP-Cap
Method: X-RAY DIFFRACTION / Resolution: 1.06 Å

Chemicals

ChemComp-HOH:
WATER

PDB-1l81:
DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME

ChemComp-FMT:
FORMIC ACID

ChemComp-GOL:
GLYCEROL

PDB-1lzo:
Plasmodium Falciparum Triosephosphate Isomerase-Phosphoglycolate Complex

ChemComp-IPA:
ISOPROPYL ALCOHOL

ChemComp-ACT:
ACETATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / ANTIGEN BINDING / AFFINITY MATURATION / SOMATIC HYPERMUTATION

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