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TitleStructural basis for the human SENP5's SUMO isoform discrimination.
Journal, issue, pagesNat Commun, Vol. 16, Page 4764-4764, Year 2025
Publish dateSep 3, 2024 (structure data deposition date)
AuthorsSanchez-Alba, L. / Ying, L. / Maletic, M.D. / De Bolos, A. / Borras-Gas, H. / Liu, B. / Varejao, N. / Amador, V. / Mulder, M.P.C. / Reverter, D.
External linksNat Commun / PubMed:40404649
MethodsX-ray diffraction
Resolution1.9 - 2.36 Å
Structure data

PDB-9gnn:
Structure of SENP5 in complex with SUMO2
Method: X-RAY DIFFRACTION / Resolution: 2.36 Å

PDB-9gnv:
Human SENP5 in complex with SUMO1
Method: X-RAY DIFFRACTION / Resolution: 2.18 Å

PDB-9gnx:
Human SENP5 in complex with SUMO1 (E67D)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-AYE:
prop-2-en-1-amine

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / SUMO / cysteine protease / SENP family / SENP / ULP

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