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Structure paper

TitleMechanism of sensor kinase CitA transmembrane signaling.
Journal, issue, pagesNat Commun, Vol. 16, Page 935-935, Year 2025
Publish dateOct 27, 2022 (structure data deposition date)
AuthorsZhang, X.C. / Xue, K. / Salvi, M. / Schomburg, B. / Mehrens, J. / Giller, K. / Stopp, M. / Weisenburger, S. / Boning, D. / Sandoghdar, V. ...Zhang, X.C. / Xue, K. / Salvi, M. / Schomburg, B. / Mehrens, J. / Giller, K. / Stopp, M. / Weisenburger, S. / Boning, D. / Sandoghdar, V. / Unden, G. / Becker, S. / Andreas, L.B. / Griesinger, C.
External linksNat Commun / PubMed:39843904
MethodsX-ray diffraction
Resolution1.61 - 2.1 Å
Structure data

PDB-8bgb:
Structure of the citrate-bound extracytoplasmic PAS domain of histidine kinase CitA from Geobacillus thermodenitrificans
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-8biy:
Citrate-free extracytoplasmic PAS domain mutant R93A of sensor histidine kinase CitA from Geobacillus thermodenitrificans
Method: X-RAY DIFFRACTION / Resolution: 1.61 Å

PDB-8bjp:
The N288D mutant cytoplasmic PAS domain of Geobacillus thermodenitrificans histidine kinase CitA
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-FLC:
CITRATE ANION

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CXS:
3-CYCLOHEXYL-1-PROPYLSULFONIC ACID / pH buffer*YM

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

Source
  • geobacillus thermodenitrificans (bacteria)
KeywordsSIGNALING PROTEIN / PAS domain / extracytoplasmic / citrate-bound / sensor histidine kinase / signal transduction / Geobacillus thermodenitrificans / CitA / sensor domain / extracytoplasmic PAS domain / R93A mutation / two-component signaling system / cytoplasmic PAS domain / histidine kinase / transmembrane signaling

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