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Structure paper

TitleA general strategy for engineering GU base pairs to facilitate RNA crystallization.
Journal, issue, pagesNucleic Acids Res., Vol. 53, Year 2025
Publish dateJul 27, 2023 (structure data deposition date)
AuthorsRen, Y. / Lin, X. / Liao, W. / Peng, X. / Deng, J. / Zhang, Z. / Zhan, J. / Zhou, Y. / Westhof, E. / Lilley, D.M.J. ...Ren, Y. / Lin, X. / Liao, W. / Peng, X. / Deng, J. / Zhang, Z. / Zhan, J. / Zhou, Y. / Westhof, E. / Lilley, D.M.J. / Wang, J. / Huang, L.
External linksNucleic Acids Res. / PubMed:39721592
MethodsX-ray diffraction
Resolution1.96 - 3.86 Å
Structure data

PDB-8k7w:
Crystal structure of Broccoli aptamer with DFHBI-1T
Method: X-RAY DIFFRACTION / Resolution: 2.24 Å

PDB-8keb:
Crystal structure of 2'-dG-III riboswitch with 2'-dG
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-8z8q:
Crystal structure of 2'-dG riboswitch
Method: X-RAY DIFFRACTION / Resolution: 3.01 Å

PDB-8z8u:
Crystal structure of LINE-1 ribozyme mutant - C39U
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

PDB-8z9k:
Crystal structure of LINE-1 ribozyme
Method: X-RAY DIFFRACTION / Resolution: 3.86 Å

PDB-8za0:
Crystal structure of OR4K15 ribozyme
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-8za4:
Crystal structure of OR4K15 ribozyme mutant - chainBDF C2U
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-8zau:
Crystal structure of a methyl transferase ribozyme mutant - C29U and A59G
Method: X-RAY DIFFRACTION / Resolution: 2.43 Å

Chemicals

ChemComp-2ZY:
(5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one

ChemComp-K:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-GNG:
2'-DEOXY-GUANOSINE

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-GUN:
GUANINE

ChemComp-BA:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

Source
  • synthetic construct (others)
  • bacillus sp. (bacteria)
  • paenibacillus (bacteria)
  • homo (humans)
  • homo sapiens (human)
KeywordsRNA / Fluorescent RNA Aptamer / Broccoli / DFHBI-1T / Riboswitch / 2'-Deoxyguanosine / 2'-dG / Aptamer / ribozyme / LINE-1 / OR4K15 / methyl transferase

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