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Structure paper

TitleStructural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system.
Journal, issue, pagesNucleic Acids Res., Vol. 52, Page 8419-8430, Year 2024
Publish dateFeb 3, 2024 (structure data deposition date)
AuthorsZhang, D. / Du, L. / Gao, H. / Yuan, C. / Lin, Z.
External linksNucleic Acids Res. / PubMed:38967023
MethodsX-ray diffraction
Resolution2.4 - 3.65 Å
Structure data

PDB-8y6z:
Crystal structure of the Marinitoga sp. Csx1-Crn2 fusion ribonuclease of type III CRISPR
Method: X-RAY DIFFRACTION / Resolution: 3.65 Å

PDB-8y75:
Crystal structure of the CARF-HTH domain of Csx1-Crn2 from Marinitoga sp.
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-8y7f:
Crystal structure of CARF domain-truncated Csx1-Crn2 from Marinitoga sp.
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

PDB-8y7g:
Crystal structure of the Marinitoga sp. Csx1-Crn2 H495A mutant in complex with cyclic-tetraadenylate (cA4)
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

Source
  • marinitoga sp. 1155 (bacteria)
KeywordsHYDROLASE / type III CRISPR / self-limiting ribonuclease / ring nuclease / Csx1 / Crn2. / Crn2

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