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Structure paper

TitleConservation of C4BP-binding sequence patterns in Streptococcus pyogenes M and Enn proteins.
Journal, issue, pagesJ. Biol. Chem., Vol. 300, Page 107478-107478, Year 2024
Publish dateJun 30, 2023 (structure data deposition date)
AuthorsKolesinski, P. / McGowan, M. / Botteaux, A. / Smeesters, P.R. / Ghosh, P.
External linksJ. Biol. Chem. / PubMed:38879009
MethodsX-ray diffraction
Resolution2.5 - 2.69 Å
Structure data

PDB-8tcb:
Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M87 protein
Method: X-RAY DIFFRACTION / Resolution: 2.69 Å

PDB-8tgt:
Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M68 protein
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • homo sapiens (human)
  • streptococcus pyogenes (bacteria)
KeywordsIMMUNE SYSTEM / immune evasion / human complement

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