タイトル | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. |
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ジャーナル・号・ページ | Proc. Natl. Acad. Sci. USA, Vol. 121, Page e2321344121-e2321344121, Year 2024 |
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掲載日 | 2024年2月9日 (構造データの登録日) |
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著者 | Min, C.K. / Nwachukwu, J.C. / Hou, Y. / Russo, R.J. / Papa, A. / Min, J. / Peng, R. / Kim, S.H. / Ziegler, Y. / Rangarajan, E.S. ...Min, C.K. / Nwachukwu, J.C. / Hou, Y. / Russo, R.J. / Papa, A. / Min, J. / Peng, R. / Kim, S.H. / Ziegler, Y. / Rangarajan, E.S. / Izard, T. / Katzenellenbogen, B.S. / Katzenellenbogen, J.A. / Nettles, K.W. |
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リンク | Proc. Natl. Acad. Sci. USA / PubMed:38830107 |
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手法 | X線回折 |
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解像度 | 1.61 - 1.86 Å |
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構造データ | PDB-8vyt: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-411 手法: X-RAY DIFFRACTION / 解像度: 1.61 Å PDB-8vyx: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-410 手法: X-RAY DIFFRACTION / 解像度: 1.69 Å PDB-8vz0: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-400 手法: X-RAY DIFFRACTION / 解像度: 1.86 Å PDB-8vz1: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-409 手法: X-RAY DIFFRACTION / 解像度: 1.82 Å PDB-8vzp: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-403 手法: X-RAY DIFFRACTION / 解像度: 1.72 Å PDB-8vzq: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-406 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-8w03: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-1154 手法: X-RAY DIFFRACTION / 解像度: 1.68 Å PDB-8w07: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-402 手法: X-RAY DIFFRACTION / 解像度: 1.83 Å |
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化合物 | PDB-1ahv: STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH 2-NITRO-P-CRESOL
PDB-1ahu: STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH P-CRESOL
PDB-1aho: THE AB INITIO STRUCTURE DETERMINATION AND REFINEMENT OF A SCORPION PROTEIN TOXIN
PDB-1ahs: CRYSTAL STRUCTURE OF THE TOP DOMAIN OF AFRICAN HORSE SICKNESS VIRUS VP7
PDB-1ahw: A COMPLEX OF EXTRACELLULAR DOMAIN OF TISSUE FACTOR WITH AN INHIBITORY FAB (5G9)
PDB-1ahx: ASPARTATE AMINOTRANSFERASE HEXAMUTANT
ChemComp-OBT: (1S,2R,4S)-N-(4-chlorophenyl)-5,6-bis(4-hydroxyphenyl)-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide
PDB-1ahy: ASPARTATE AMINOTRANSFERASE HEXAMUTANT
PDB-1ahz: STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH 4-(1-HEPTENYL)PHENOL
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由来 | - homo sapiens (ヒト)
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キーワード | NUCLEAR PROTEIN / Estrogen Receptor / Estrogen Receptor Alpha |
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