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Structure paper

TitleStructure and function of Semaphorin-5A glycosaminoglycan interactions.
Journal, issue, pagesNat Commun, Vol. 15, Page 2723-2723, Year 2024
Publish dateFeb 15, 2023 (structure data deposition date)
AuthorsNagy, G.N. / Zhao, X.F. / Karlsson, R. / Wang, K. / Duman, R. / Harlos, K. / El Omari, K. / Wagner, A. / Clausen, H. / Miller, R.L. ...Nagy, G.N. / Zhao, X.F. / Karlsson, R. / Wang, K. / Duman, R. / Harlos, K. / El Omari, K. / Wagner, A. / Clausen, H. / Miller, R.L. / Giger, R.J. / Jones, E.Y.
External linksNat Commun / PubMed:38548715
MethodsX-ray diffraction
Resolution1.56 - 2.72 Å
Structure data

PDB-8ckg:
Semaphorin-5A TSR 3-4 domains in complex with sulfate
Method: X-RAY DIFFRACTION / Resolution: 1.714 Å

PDB-8ckk:
Semaphorin-5A TSR 3-4 domains in complex with nitrate
Method: X-RAY DIFFRACTION / Resolution: 1.56 Å

PDB-8ckl:
Semaphorin-5A TSR 3-4 domains in complex with sucrose octasulfate (SOS)
Method: X-RAY DIFFRACTION / Resolution: 2.56 Å

PDB-8ckm:
Semaphorin-5A TSR 3-4 domains
Method: X-RAY DIFFRACTION / Resolution: 2.72 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-HOH:
WATER

ChemComp-NO3:
NITRATE ION

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / semaphorin / cell signalling / axon guidance cue / glycosaminoglycan binding protein

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