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Structure paper

TitleTargeting protein-protein interaction interfaces with antiviral N protein inhibitor in SARS-CoV-2.
Journal, issue, pagesBiophys. J., Vol. 123, Page 478-488, Year 2024
Publish dateMar 16, 2023 (structure data deposition date)
AuthorsHong, J.Y. / Lin, S.C. / Kehn-Hall, K. / Zhang, K.M. / Luo, S.Y. / Wu, H.Y. / Chang, S.Y. / Hou, M.H.
External linksBiophys. J. / PubMed:38234090
MethodsX-ray diffraction
Resolution1.9 - 2.7 Å
Structure data

PDB-8iqj:
Crystal structure of SARS-CoV2 N-NTD
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-8iv3:
Crystal structure of SARS-CoV2 N-NTD complexed with 5-Benzyloxygramine
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-8j6x:
Crystal structure of SARS-CoV2 N-NTD complexed with 5-Benzyloxygramine derivative (P3-8)
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-DJU:
N,N-dimethyl-1-(5-phenylmethoxy-1H-indol-3-yl)methanamine


ChemComp, No image

ChemComp-U2H:
Unknown entry

Source
  • severe acute respiratory syndrome coronavirus 2
KeywordsVIRAL PROTEIN / nucleocapsid protein / Severe acute respiratory syndrome coronavirus 2 nucleocapsid protein 5-Benzyloxygramine

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