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-Structure paper
Title | Discovery of a Biotin Synthase That Utilizes an Auxiliary 4Fe-5S Cluster for Sulfur Insertion. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 146, Page 1860-1873, Year 2024 |
Publish date | Dec 14, 2023 (structure data deposition date) |
Authors | Lachowicz, J.C. / Lennox-Hvenekilde, D. / Myling-Petersen, N. / Salomonsen, B. / Verkleij, G. / Acevedo-Rocha, C.G. / Caddell, B. / Gronenberg, L.S. / Almo, S.C. / Sommer, M.O.A. ...Lachowicz, J.C. / Lennox-Hvenekilde, D. / Myling-Petersen, N. / Salomonsen, B. / Verkleij, G. / Acevedo-Rocha, C.G. / Caddell, B. / Gronenberg, L.S. / Almo, S.C. / Sommer, M.O.A. / Genee, H.J. / Grove, T.L. |
External links | J. Am. Chem. Soc. / PubMed:38215281 |
Methods | X-ray diffraction |
Resolution | 1.35 - 1.807 Å |
Structure data | PDB-8vcw: PDB-8vdw: |
Chemicals | ChemComp-SAM: ChemComp-BTB: ChemComp-Q46: ChemComp-SF4: ChemComp-DTB: ChemComp-FE: ChemComp-CL: ChemComp-HOH: ChemComp-NA: |
Source |
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Keywords | TRANSFERASE / biotin / iron sulfur cluster / desthiobiotin / radical SAM / iron-sulfur cluster / sulfur insertion / 4 iron-5 sulfur cluster |