タイトル | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. |
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ジャーナル・号・ページ | Nature, Vol. 621, Page 840-848, Year 2023 |
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掲載日 | 2022年11月23日 (構造データの登録日) |
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著者 | Yuan, L. / Ma, X. / Yang, Y. / Qu, Y. / Li, X. / Zhu, X. / Ma, W. / Duan, J. / Xue, J. / Yang, H. ...Yuan, L. / Ma, X. / Yang, Y. / Qu, Y. / Li, X. / Zhu, X. / Ma, W. / Duan, J. / Xue, J. / Yang, H. / Huang, J.W. / Yi, S. / Zhang, M. / Cai, N. / Zhang, L. / Ding, Q. / Lai, K. / Liu, C. / Liu, X. / Yao, Y. / Zhou, S. / Shen, P. / Chang, Q. / Malwal, S.R. / He, Y. / Li, W. / Chen, C. / Chen, C.C. / Oldfield, E. / Guo, R.T. / Zhang, Y. |
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リンク | Nature / PubMed:37674084 |
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手法 | X線回折 |
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解像度 | 1.4 - 2.91 Å |
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構造データ | PDB-8hjt: Crystal Structure of Intracellular B30.2 Domain of VpBTN3 and VpBTN2 in Complex with HMBPP 手法: X-RAY DIFFRACTION / 解像度: 2.91 Å PDB-8igt: Crystal Structure of Intracellular B30.2 Domain of BTN2A1 手法: X-RAY DIFFRACTION / 解像度: 1.56 Å PDB-8ih4: Crystal Structure of Intracellular B30.2 Domain of BTN2A2 Mutant 手法: X-RAY DIFFRACTION / 解像度: 2.12 Å PDB-8ixv: Crystal structure of intracellular B30.2 domain of BTN3A in complex with 2Cl-HMBPP 手法: X-RAY DIFFRACTION / 解像度: 1.72 Å PDB-8ize: Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with 4-HMBPP 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-8izg: Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with 5-HMBPP 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-8jy9: Crystal Structure of Intracellular B30.2 Domain of VpBTN3 in Complex with HMBPP 手法: X-RAY DIFFRACTION / 解像度: 1.83 Å PDB-8jya: Crystal Structure of Intracellular B30.2 Domain of VpBTN3 in Complex with IPP 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-8jyb: Crystal Structure of Intracellular B30.2 Domain of VpBTN3 手法: X-RAY DIFFRACTION / 解像度: 1.91 Å PDB-8jyc: Crystal Structure of Intracellular B30.2 Domain of BTN3A1 and BTN2A1 in Complex with DMAPP 手法: X-RAY DIFFRACTION / 解像度: 2.29 Å PDB-8jye: Crystal Structure of Intracellular B30.2 Domain of BTN3A1 and BTN2A1 in Complex with HMBPP 手法: X-RAY DIFFRACTION / 解像度: 2.18 Å PDB-8jyf: Crystal Structure of Intracellular B30.2 Domain of VpBTN3 in Complex with DMAPP 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å |
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化合物 | ChemComp-H6P: (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate / HMBPP
ChemComp-EPE: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / HEPES / pH緩衝剤*YM
ChemComp-RZO: [bis(chloranyl)-[[(E)-3-methyl-4-oxidanyl-but-2-enoxy]-oxidanyl-phosphoryl]methyl]phosphonic acid
ChemComp-S9R: [(E)-3-(hydroxymethyl)pent-2-enyl] phosphono hydrogen phosphate
ChemComp-SE6: [(2E)-3-(hydroxymethyl)hexa-2,5-dienyl] phosphono hydrogen phosphate
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由来 | - vicugna pacos (アルパカ)
- homo sapiens (ヒト)
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キーワード | IMMUNE SYSTEM / Butyrophilin / Signaling Protein |
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