タイトル | Reprogramming the Cyclization Cascade of epi -Isozizaene Synthase to Generate Alternative Terpene Products. |
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ジャーナル・号・ページ | Biochemistry, Vol. 62, Page 2301-2313, Year 2023 |
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掲載日 | 2023年5月11日 (構造データの登録日) |
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著者 | Eaton, S.A. / Christianson, D.W. |
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リンク | Biochemistry / PubMed:37449555 |
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手法 | X線回折 |
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解像度 | 1.29 - 1.99 Å |
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構造データ | PDB-8su0: Unliganded F96H epi-Isozizaene Synthase 手法: X-RAY DIFFRACTION / 解像度: 1.99 Å PDB-8su1: F96H epi-Isozizaene Synthase: complex with 3 Mg2+ and pamidronate 手法: X-RAY DIFFRACTION / 解像度: 1.37 Å PDB-8su2: F96H epi-Isozizaene Synthase: complex with 3 Mg2+ and risedronate 手法: X-RAY DIFFRACTION / 解像度: 1.33 Å PDB-8su3: F95S epi-Isozizaene Synthase: complex with 3 Mg2+, inorganic pyrophosphate, and benzyl triethyl ammonium cation 手法: X-RAY DIFFRACTION / 解像度: 1.29 Å PDB-8su4: F198S epi-Isozizaene Synthase: complex with 3 Mg2+, inorganic pyrophosphate, and benzyl triethyl ammonium cation 手法: X-RAY DIFFRACTION / 解像度: 1.43 Å PDB-8su5: F198T epi-Isozizaene Synthase: complex with 3 Mg2+, inorganic pyrophosphate, and benzyl triethyl ammonium cation 手法: X-RAY DIFFRACTION / 解像度: 1.48 Å |
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化合物 | |
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由来 | streptomyces coelicolor a3(2) (バクテリア)
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キーワード | LYASE / Terpene / Terpenoid / Isoprenoid / Terpene cyclase / Terpene synthase |
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