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Structure paper

TitleCross-β helical filaments of Tau and TMEM106B in gray and white matter of multiple system tauopathy with presenile dementia.
Journal, issue, pagesActa Neuropathol, Vol. 145, Issue 5, Page 707-710, Year 2023
Publish dateMar 23, 2023
AuthorsMd Rejaul Hoq / Sakshibeedu R Bharath / Grace I Hallinan / Anllely Fernandez / Frank S Vago / Kadir A Ozcan / Daoyi Li / Holly J Garringer / Ruben Vidal / Bernardino Ghetti / Wen Jiang /
External linksActa Neuropathol / PubMed:36952000 / PubMed Central
MethodsEM (helical sym.)
Resolution3.25 - 3.4 Å
Structure data

25995

7tmc

EMDB-25995, PDB-7tmc:
TMEM106B singlet filament extracted from MSTD neurodegenerative human brain
Method: EM (helical sym.) / Resolution: 3.25 Å

28943

8f9k

EMDB-28943, PDB-8f9k:
TMEM106B doublet filaments extracted from MSTD neurodegenerative human brain
Method: EM (helical sym.) / Resolution: 3.4 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsNEUROPEPTIDE / TMEM106B / TMEM filament / MSTD

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