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-Structure paper
Title | Discovery of small molecules that target a tertiary-structured RNA. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 119, Page e2213117119-e2213117119, Year 2022 |
Publish date | May 28, 2022 (structure data deposition date) |
Authors | Menichelli, E. / Lam, B.J. / Wang, Y. / Wang, V.S. / Shaffer, J. / Tjhung, K.F. / Bursulaya, B. / Nguyen, T.N. / Vo, T. / Alper, P.B. ...Menichelli, E. / Lam, B.J. / Wang, Y. / Wang, V.S. / Shaffer, J. / Tjhung, K.F. / Bursulaya, B. / Nguyen, T.N. / Vo, T. / Alper, P.B. / McAllister, C.S. / Jones, D.H. / Spraggon, G. / Michellys, P.Y. / Joslin, J. / Joyce, G.F. / Rogers, J. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:36413497 |
Methods | X-ray diffraction |
Resolution | 1.42 - 2.7 Å |
Structure data | PDB-8d28: PDB-8d29: PDB-8d2a: PDB-8d2b: PDB-8d5l: PDB-8d5o: PDB-8dk7: |
Chemicals | ChemComp-TEP: ChemComp-MG: ChemComp-NA: ChemComp-HOH: ChemComp-K: ChemComp-QB3: ChemComp-QAX: ChemComp-QIJ: ChemComp-CA: ChemComp-QEU: |
Source |
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Keywords | RNA / aptamer / theophylline / RNA/IMMUNE SYSTEM / RNA-IMMUNE SYSTEM complex |