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TitleAntigenic mapping reveals sites of vulnerability on alpha-HCoV spike protein.
Journal, issue, pagesCommun Biol, Vol. 5, Page 1179-1179, Year 2022
Publish dateOct 10, 2021 (structure data deposition date)
AuthorsXiang, J. / Su, J. / Lan, Q. / Zhao, W. / Zhou, Y. / Xu, Y. / Niu, J. / Xia, S. / Qi, Q. / Sidhu, S. ...Xiang, J. / Su, J. / Lan, Q. / Zhao, W. / Zhou, Y. / Xu, Y. / Niu, J. / Xia, S. / Qi, Q. / Sidhu, S. / Lu, L. / Miersch, S. / Yang, B.
External linksCommun Biol / PubMed:36333470
MethodsX-ray diffraction
Resolution2.85 - 4.49 Å
Structure data

PDB-7vmz:
Crystal structure of a human Coronavirus 229E antibody C04 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-7vn9:
Crystal structure of human coronavirus 229E spike protein receptor-binding domain in complex with C04 Fab
Method: X-RAY DIFFRACTION / Resolution: 4.49 Å

PDB-7vng:
Crystal structure of human coronavirus 229E spike protein receptor-binding domain in complex with S11 Fab
Method: X-RAY DIFFRACTION / Resolution: 3.8 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • human coronavirus 229e
KeywordsIMMUNE SYSTEM / the antibody C04 targeted RBD of human Coronavirus 229E spike / VIRAL PROTEIN/IMMUNE SYSTEM / Neutralizing antibody / human coronavirus 229E / C04 Fab. / VIRAL PROTEIN-IMMUNE SYSTEM complex / spike protein / RBD / antibody / S11

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