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-Structure paper
Title | Small-molecule inhibition of the archetypal UbiB protein COQ8. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 19, Page 230-238, Year 2023 |
Publish date | Mar 20, 2022 (structure data deposition date) |
Authors | Murray, N.H. / Asquith, C.R.M. / Fang, Z. / East, M.P. / Ptak, N. / Smith, R.W. / Vasta, J.D. / Zimprich, C.A. / Corona, C.R. / Robers, M.B. ...Murray, N.H. / Asquith, C.R.M. / Fang, Z. / East, M.P. / Ptak, N. / Smith, R.W. / Vasta, J.D. / Zimprich, C.A. / Corona, C.R. / Robers, M.B. / Johnson, G.L. / Bingman, C.A. / Pagliarini, D.J. |
External links | Nat. Chem. Biol. / PubMed:36302899 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.01 Å |
Structure data | PDB-7udp: PDB-7udq: |
Chemicals | ChemComp-MVS: ChemComp-HOH: ChemComp-NA: |
Source |
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Keywords | TRANSFERASE / CoQ biosynthesis / kinase-like / TRANSFERASE/TRANSFERASE INHIBITOR / TRANSFERASE-TRANSFERASE INHIBITOR complex |