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Structure paper

TitleA conserved signaling pathway activates bacterial CBASS immune signaling in response to DNA damage.
Journal, issue, pagesEmbo J., Vol. 41, Page e111540-e111540, Year 2022
Publish dateDec 13, 2021 (structure data deposition date)
AuthorsLau, R.K. / Enustun, E. / Gu, Y. / Nguyen, J.V. / Corbett, K.D.
External linksEmbo J. / PubMed:36156805
MethodsX-ray diffraction
Resolution1.02 - 1.75 Å
Structure data

PDB-7t5t:
Structure of Thauera sp. K11 CapP
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-7t5u:
Structure of E. coli MS115-1 CapH N-terminal domain
Method: X-RAY DIFFRACTION / Resolution: 1.02 Å

PDB-7t5v:
Structure of E. coli CapH C-terminal domain I99M mutant
Method: X-RAY DIFFRACTION / Resolution: 1.26 Å

PDB-7t5w:
Structure of E. coli CapH C-terminal domain
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-NHE:
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID / pH buffer*YM

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • thauera sp. k11 (bacteria)
  • escherichia coli (E. coli)
KeywordsHYDROLASE / Zinc metallopeptidase / IrrE / cysteine switch / DNA BINDING PROTEIN / Helix turn helix / HTH / DdrO

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