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Structure paper

TitleObservation of conformational changes that underlie the catalytic cycle of Xrn2.
Journal, issue, pagesNat. Chem. Biol., Vol. 18, Page 1152-1160, Year 2022
Publish dateJun 1, 2021 (structure data deposition date)
AuthorsOverbeck, J.H. / Stelzig, D. / Fuchs, A.L. / Wurm, J.P. / Sprangers, R.
External linksNat. Chem. Biol. / PubMed:36008487
MethodsX-ray diffraction / NMR (solution)
Resolution3 Å
Structure data

PDB-7opk:
Crystal structure of C. thermophilum Xrn2
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-7pvm:
NMR structure of the C. thermophilum Xrn2 zinc finger
Method: SOLUTION NMR

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ZN:
Unknown entry

Source
  • chaetomium thermophilum (strain dsm 1495 / cbs 144.50 / imi 039719) (fungus)
KeywordsRNA / degradation / metabolism / hydrolysis / RNA BINDING PROTEIN / Zinc finger

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