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-Structure paper
| Title | Substitution of the Methionine Axial Ligand of the T1 Copper for the Fungal-like Phenylalanine Ligand (M298F) Causes Local Structural Perturbations that Lead to Thermal Instability and Reduced Catalytic Efficiency of the Small Laccase from Streptomyces coelicolor A3(2). |
|---|---|
| Journal, issue, pages | Acs Omega, Vol. 7, Page 6184-6194, Year 2022 |
| Publish date | Nov 27, 2020 (structure data deposition date) |
Authors | Zovo, K. / Pupart, H. / Van Wieren, A. / Gillilan, R.E. / Huang, Q. / Majumdar, S. / Lukk, T. |
External links | Acs Omega / PubMed:35224382 |
| Methods | X-ray diffraction |
| Resolution | 2 - 2.7 Å |
| Structure data | ![]() PDB-7b2k: ![]() PDB-7b4y: ![]() PDB-7bdn: ![]() PDB-7bfm: |
| Chemicals | ![]() ChemComp-CU: ![]() ChemComp-HOH: ![]() ChemComp-PG4: |
| Source |
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Keywords | OXIDOREDUCTASE / small laccase / T1 copper / point mutation / M298F / M298L / cubic crystal form / double mutant / M198F M298F |
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streptomyces coelicolor (strain atcc baa-471 / a3(2) / m145) (bacteria)
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