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-Structure paper
Title | Substitution of the Methionine Axial Ligand of the T1 Copper for the Fungal-like Phenylalanine Ligand (M298F) Causes Local Structural Perturbations that Lead to Thermal Instability and Reduced Catalytic Efficiency of the Small Laccase from Streptomyces coelicolor A3(2). |
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Journal, issue, pages | Acs Omega, Vol. 7, Page 6184-6194, Year 2022 |
Publish date | Nov 27, 2020 (structure data deposition date) |
Authors | Zovo, K. / Pupart, H. / Van Wieren, A. / Gillilan, R.E. / Huang, Q. / Majumdar, S. / Lukk, T. |
External links | Acs Omega / PubMed:35224382 |
Methods | X-ray diffraction |
Resolution | 2 - 2.7 Å |
Structure data | PDB-7b2k: PDB-7b4y: PDB-7bdn: PDB-7bfm: |
Chemicals | ChemComp-CU: ChemComp-HOH: ChemComp-PG4: |
Source |
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Keywords | OXIDOREDUCTASE / small laccase / T1 copper / point mutation / M298F / M298L / cubic crystal form / double mutant / M198F M298F |