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Structure paper

TitleMLL1 is regulated by KSHV LANA and is important for virus latency.
Journal, issue, pagesNucleic Acids Res., Vol. 49, Page 12895-12911, Year 2021
Publish dateDec 21, 2020 (structure data deposition date)
AuthorsTan, M. / Li, S. / Juillard, F. / Chitas, R. / Custodio, T.F. / Xue, H. / Szymula, A. / Sun, Q. / Liu, B. / Alvarez, A.L. ...Tan, M. / Li, S. / Juillard, F. / Chitas, R. / Custodio, T.F. / Xue, H. / Szymula, A. / Sun, Q. / Liu, B. / Alvarez, A.L. / Chen, S. / Huang, J. / Simas, J.P. / McVey, C.E. / Kaye, K.M.
External linksNucleic Acids Res. / PubMed:34850113
MethodsX-ray diffraction
Resolution1.26 - 1.5 Å
Structure data

PDB-7bcy:
X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-7bed:
X-ray structure of WDR5 bound to the WDR5 win motif peptide
Method: X-RAY DIFFRACTION / Resolution: 1.26 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
  • human herpesvirus 8 type m
KeywordsTRANSFERASE / WD repeat-containing protein 5 LANA Histone Methyltransferase H3K4 / TRANSCRIPTION

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