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TitleInteractions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release.
Journal, issue, pagesJ. Biol. Chem., Vol. 297, Page 100975-100975, Year 2021
Publish dateFeb 11, 2021 (structure data deposition date)
AuthorsRheinemann, L. / Thompson, T. / Mercenne, G. / Paine, E.L. / Peterson, F.C. / Volkman, B.F. / Alam, S.L. / Alian, A. / Sundquist, W.I.
External linksJ. Biol. Chem. / PubMed:34284061
MethodsX-ray diffraction / NMR (solution)
Resolution1.35 - 1.88 Å
Structure data

PDB-7lp1:
Structure of Nedd4L WW3 domain
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-7lp2:
Structure of Nedd4L WW3 domain
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

PDB-7lp3:
Structure of Nedd4L WW3 domain
Method: X-RAY DIFFRACTION / Resolution: 1.61 Å

PDB-7lp4:
Structure of Nedd4L WW3 domain
Method: SOLUTION NMR

PDB-7lp5:
Structure of Nedd4L WW3 domain
Method: SOLUTION NMR

Chemicals

ChemComp-NO3:
NITRATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsLIGASE / PPxY binding / E3 Ubiquitin ligase / Nedd4L / WW domain

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