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TitleStructural insights into the functional divergence of WhiB-like proteins in Mycobacterium tuberculosis.
Journal, issue, pagesMol. Cell, Vol. 81, Page 2887-, Year 2021
Publish dateNov 24, 2020 (structure data deposition date)
AuthorsWan, T. / Horova, M. / Beltran, D.G. / Li, S. / Wong, H.X. / Zhang, L.M.
External linksMol. Cell / PubMed:34171298
MethodsX-ray diffraction
Resolution1.55 - 2.6 Å
Structure data

PDB-7kuf:
Transcription activation subcomplex with WhiB7 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-7kug:
Fe-S cluster-bound transcription activator WhiB7 in complex with the SigmaAr4-RNAP Beta flap tip chimera
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
  • mycobacterium tuberculosis (strain atcc 25618 / h37rv) (bacteria)
KeywordsTRANSCRIPTION / Redox-sensitive / Iron-sulfur cluster / activator

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