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Structure paper

TitleStructural characterization of KKT4, an unconventional microtubule-binding kinetochore protein.
Journal, issue, pagesStructure, Vol. 29, Page 1014-1028.e8, Year 2021
Publish dateJul 8, 2020 (structure data deposition date)
AuthorsLudzia, P. / Lowe, E.D. / Marciano, G. / Mohammed, S. / Redfield, C. / Akiyoshi, B.
External linksStructure / PubMed:33915106
MethodsX-ray diffraction
Resolution1.57 - 1.9 Å
Structure data

PDB-6zpj:
Crystal structure of the unconventional kinetochore protein Leishmania mexicana KKT4 coiled coil domain
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-6zpk:
Crystal structure of the unconventional kinetochore protein Trypanosoma brucei KKT4 BRCT domain
Method: X-RAY DIFFRACTION / Resolution: 1.57 Å

PDB-6zpm:
Crystal structure of the unconventional kinetochore protein Trypanosoma cruzi KKT4 coiled coil domain
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-IMD:
IMIDAZOLE

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-THR:
THREONINE

Source
  • leishmania mexicana (strain mhom/gt/2001/u1103) (eukaryote)
  • trypanosoma brucei brucei (strain 927/4 gutat10.1) (eukaryote)
  • trypanosoma cruzi (eukaryote)
KeywordsCELL CYCLE / kinetochore / kinetoplastid / microtubules / coiled coil / KKT4 / BRCT / kinetoplastids

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