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TitleHuman antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis.
Journal, issue, pagesNat Commun, Vol. 12, Page 602-602, Year 2021
Publish dateDec 1, 2020 (structure data deposition date)
AuthorsWatson, A. / Li, H. / Ma, B. / Weiss, R. / Bendayan, D. / Abramovitz, L. / Ben-Shalom, N. / Mor, M. / Pinko, E. / Bar Oz, M. ...Watson, A. / Li, H. / Ma, B. / Weiss, R. / Bendayan, D. / Abramovitz, L. / Ben-Shalom, N. / Mor, M. / Pinko, E. / Bar Oz, M. / Wang, Z. / Du, F. / Lu, Y. / Rybniker, J. / Dahan, R. / Huang, H. / Barkan, D. / Xiang, Y. / Javid, B. / Freund, N.T.
External linksNat Commun / PubMed:33504803
MethodsX-ray diffraction
Resolution2.1 - 2.4 Å
Structure data

PDB-7dm1:
crystal structure of the M.tuberculosis phosphate ABC transport receptor PstS-1 in complex with Fab p4-36
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-7dm2:
crystal structure of the M. tuberculosis phosphate ABC transport receptor PstS-1 in complex with Fab p4-170
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis h37rv (bacteria)
  • homo sapiens (human)
KeywordsTRANSPROT PROTEIN/IMMUNE SYSTEM / antibody / complex / TRANSPORT PROTEIN / TRANSPROT PROTEIN-IMMUNE SYSTEM complex / TRANSPORT PROTEIN/IMMUNE SYSTEM / TRANSPORT PROTEIN-IMMUNE SYSTEM complex

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