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Structure paper

TitleGenetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction.
Journal, issue, pagesNat Commun, Vol. 12, Page 581-581, Year 2021
Publish dateApr 27, 2020 (structure data deposition date)
AuthorsZhu, R. / Zhang, G. / Jing, M. / Han, Y. / Li, J. / Zhao, J. / Li, Y. / Chen, P.R.
External linksNat Commun / PubMed:33495458
MethodsX-ray diffraction
Resolution1.658 - 2.9 Å
Structure data

PDB-7bzd:
Structure of Bacillus subtilis HxlR, wild type
Method: X-RAY DIFFRACTION / Resolution: 2.612 Å

PDB-7bze:
Structure of Bacillus subtilis HxlR, K13A mutant
Method: X-RAY DIFFRACTION / Resolution: 1.658 Å

PDB-7bzg:
Structure of Bacillus subtilis HxlR, wild type in complex with formaldehyde and DNA
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-FOR:
FORMYL GROUP

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-MG:
Unknown entry

ChemComp-PE8:
3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL

Source
  • bacillus subtilis (strain 168) (bacteria)
  • bacillus subtilis subsp. subtilis str. 168 (bacteria)
KeywordsDNA BINDING PROTEIN / Transcriptional regulator / formaldehyde sensing / DNA BINDING PROTEIN-DNA complex

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