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TitleRecognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.
Journal, issue, pagesMbio, Vol. 11, Year 2020
Publish dateJul 6, 2012 (structure data deposition date)
AuthorsTolbert, W.D. / Van, V. / Sherburn, R. / Tuyishime, M. / Yan, F. / Nguyen, D.N. / Stanfield-Oakley, S. / Easterhoff, D. / Bonsignori, M. / Haynes, B.F. ...Tolbert, W.D. / Van, V. / Sherburn, R. / Tuyishime, M. / Yan, F. / Nguyen, D.N. / Stanfield-Oakley, S. / Easterhoff, D. / Bonsignori, M. / Haynes, B.F. / Moody, M.A. / Ray, K. / Ferrari, G. / Lewis, G.K. / Pazgier, M.
External linksMbio / PubMed:32605979
MethodsX-ray diffraction
Resolution2.461 - 3.85 Å
Structure data

PDB-4fz8:
Crystal structure of C11 Fab, an ADCC mediating anti-HIV-1 antibody.
Method: X-RAY DIFFRACTION / Resolution: 2.66 Å

PDB-6mg7:
Crystal structure of the RV144 C1-C2 specific antibody CH54 Fab in complex with HIV-1 CLADE A/E GP120 and M48U1
Method: X-RAY DIFFRACTION / Resolution: 2.91 Å

PDB-6oed:
CRYSTAL STRUCTURE OF THE RV144 C1-C2 SPECIFIC ANTIBODY CH55 FAB
Method: X-RAY DIFFRACTION / Resolution: 2.461 Å

PDB-6oej:
CRYSTAL STRUCTURE OF THE NON-NEUTRALIZING AND ADCC-POTENT ANTIBODY C11 IN COMPLEX WITH HIV-1 CLADE A/E GP120
Method: X-RAY DIFFRACTION / Resolution: 3.45 Å

PDB-6ofi:
CRYSTAL STRUCTURE OF the RV144 C1-C2 SPECIFIC ANTIBODY CH55 FAB IN COMPLEX WITH HIV-1 CLADE A/E GP120
Method: X-RAY DIFFRACTION / Resolution: 3.85 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human immunodeficiency virus 1
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / ADCC / ANTI-HIV-1 ENV ANTIBODY C11 / CD4I ANTIBODY / FAB / VIRAL GLYCOPROTEIN GP120 / HIV-1 ENV / VIRAL PROTEIN/IMMUNE SYSTEM / ANTI-HIV-1 ENV ANTIBODY CH54 / RV144 VACCINE TRIAL / CLADE A/E 93TH057 / VIRAL PROTEIN-IMMUNE SYSTEM complex / ANTI-HIV-1 ENV ANTIBODY CH55 / HIV-1 GP120 / VIRAL PROTEIN

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