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TitleCBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection.
Journal, issue, pagesCell, Vol. 182, Page 38-, Year 2020
Publish dateJan 27, 2020 (structure data deposition date)
AuthorsLowey, B. / Whiteley, A.T. / Keszei, A.F.A. / Morehouse, B.R. / Mathews, I.T. / Antine, S.P. / Cabrera, V.J. / Kashin, D. / Niemann, P. / Jain, M. ...Lowey, B. / Whiteley, A.T. / Keszei, A.F.A. / Morehouse, B.R. / Mathews, I.T. / Antine, S.P. / Cabrera, V.J. / Kashin, D. / Niemann, P. / Jain, M. / Schwede, F. / Mekalanos, J.J. / Shao, S. / Lee, A.S.Y. / Kranzusch, P.J.
External linksCell / PubMed:32544385
MethodsX-ray diffraction
Resolution2.1 - 2.6 Å
Structure data

PDB-6vm5:
Structure of Moraxella osloensis Cap4 SAVED/CARF-domain containing receptor
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-6vm6:
Structure of Acinetobacter baumannii Cap4 SAVED/CARF-domain containing receptor with the cyclic trinucleotide 2'3'3'-cAAA
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6wam:
Structure of Acinetobacter baumannii Cap4 SAVED/CARF-domain containing receptor
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-6wan:
Structure of Acinetobacter baumannii Cap4 SAVED/CARF-domain containing receptor with the cyclic trinucleotide 3'3'3'-cAAA
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • moraxella osloensis (bacteria)
  • acinetobacter sp. atcc 27244 (bacteria)
  • synthetic construct (others)
  • acinetobacter baumannii (bacteria)
KeywordsHYDROLASE / nuclease / DUF4297 / SAVED / CARF / phage immunity

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