タイトル | Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. |
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ジャーナル・号・ページ | Mol. Biol. Cell, Vol. 31, Page 1879-1891, Year 2020 |
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掲載日 | 2020年5月20日 (構造データの登録日) |
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著者 | Baumhardt, J.M. / Walker, J.S. / Lee, Y. / Shakya, B. / Brautigam, C.A. / Lapalombella, R. / Grishin, N. / Chook, Y.M. |
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リンク | Mol. Biol. Cell / PubMed:32520643 |
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手法 | X線回折 |
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解像度 | 2.2 - 3.001 Å |
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構造データ | PDB-6x2m: Crystal Structure of unliganded CRM1-Ran-RanBP1 手法: X-RAY DIFFRACTION / 解像度: 2.351 Å PDB-6x2o: Crystal Structure of unliganded CRM1(E571K)-Ran-RanBP1 手法: X-RAY DIFFRACTION / 解像度: 2.551 Å PDB-6x2p: Crystal Structure of the Mek1NES peptide bound to CRM1 手法: X-RAY DIFFRACTION / 解像度: 2.401 Å PDB-6x2r: Crystal Structure of the 4E-TNES peptide bound to CRM1 手法: X-RAY DIFFRACTION / 解像度: 2.299 Å PDB-6x2s: Crystal Structure of Mek1(NQ)NES peptide bound to CRM 手法: X-RAY DIFFRACTION / 解像度: 2.496 Å PDB-6x2u: Crystal Structure of PKINES peptide bound to CRM1 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-6x2v: Crystal Structure of PKI(DE)NES peptide bound to CRM1 手法: X-RAY DIFFRACTION / 解像度: 2.822 Å PDB-6x2w: Crystal Structure of PKINES peptide bound to CRM1(E571K) 手法: X-RAY DIFFRACTION / 解像度: 3.001 Å PDB-6x2x: Crystal Structure of Mek1NES peptide bound to CRM1(E571K) 手法: X-RAY DIFFRACTION / 解像度: 2.458 Å PDB-6x2y: Crystal Structure of mDia2NES peptide bound to CRM1(E571K) 手法: X-RAY DIFFRACTION / 解像度: 2.304 Å |
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化合物 | ChemComp-GNP: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / Gpp(NH)p / GppNHp, GMPPNP, エネルギー貯蔵分子類似体*YM
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由来 | - homo sapiens (ヒト)
- saccharomyces cerevisiae (パン酵母)
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キーワード | PROTEIN TRANSPORT / Nuclear export / CRM1 / XPO1 / Exportin-1 |
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