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Structure paper

TitleMolecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 6550-6558, Year 2020
Publish dateMay 13, 2019 (structure data deposition date)
AuthorsCho, J.H. / Zhao, B. / Shi, J. / Savage, N. / Shen, Q. / Byrnes, J. / Yang, L. / Hwang, W. / Li, P.
External linksProc. Natl. Acad. Sci. USA / PubMed:32152123
MethodsX-ray diffraction
Resolution2.75 - 2.95 Å
Structure data

PDB-6ox7:
The complex of 1918 NS1-ED and the iSH2 domain of the human p85beta subunit of PI3K
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-6u28:
Crystal structure of 1918 NS1-ED W187A in complex with the p85-beta-iSH2 domain of human PI3K
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • influenza a virus (strain a/brevig mission/1/1918 h1n1)
  • homo sapiens (human)
KeywordsVIRAL PROTEIN / NS1 / p85-beta / PI3K / 1918 / 1918 influenza A virus

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